Estranged from his family, Jonathan (Garrett Hedlund) discovers his father has decided to take himself off life support in forty-eight hours' time. During this intensely condensed period, a lifetime of drama plays out. Robert (Richard Jenkins) fights a zero sum game to reclaim all that his illness stole from his family. A debate rages on patients' rights and what it truly means to be free. Jonathan reconciles with his father, reconnects with his mother (Anne Archer), sister (Jessica Brown-Findlay), and his love (Amy Adams) and reclaims his voice through two unlikely catalysts - a young, wise-beyond-her-years patient (Jessica Barden) and a no-nonsense nurse (Jennifer Hudson). Through this intensely life affirming prism, an unexpected and powerful journey of love, laughter, and forgiveness unfolds.